Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.
Identifieur interne : 000064 ( Main/Exploration ); précédent : 000063; suivant : 000065Titanium Dioxide in Toothpaste Causing Yellow Nail Syndrome.
Auteurs : Ting-Yuan Hsu [Taïwan] ; Chun-Chen Lin [Taïwan] ; Ming-Dar Lee [Taïwan] ; Brian Pin-Hsuan Chang [Taïwan] ; Jeng-Daw Tsai [Taïwan]Source :
- Pediatrics [ 1098-4275 ] ; 2017.
Descripteurs français
- KwdFr :
- Diagnostic différentiel, Dilatation des bronches (), Dilatation des bronches (diagnostic), Enfant, Femelle, Humains, Ongles (), Pâtes dentifrices (), Pâtes dentifrices (toxicité), Sinusite maxillaire (), Sinusite maxillaire (diagnostic), Syndrome des ongles jaunes (), Syndrome des ongles jaunes (diagnostic), Titane (analyse), Titane (toxicité).
- MESH :
- analyse : Titane.
- diagnostic : Dilatation des bronches, Sinusite maxillaire, Syndrome des ongles jaunes.
- toxicité : Pâtes dentifrices, Titane.
- Diagnostic différentiel, Dilatation des bronches, Enfant, Femelle, Humains, Ongles, Pâtes dentifrices, Sinusite maxillaire, Syndrome des ongles jaunes.
English descriptors
- KwdEn :
- Bronchiectasis (chemically induced), Bronchiectasis (diagnosis), Child, Diagnosis, Differential, Female, Humans, Maxillary Sinusitis (chemically induced), Maxillary Sinusitis (diagnosis), Nails (chemistry), Titanium (analysis), Titanium (toxicity), Toothpastes (chemistry), Toothpastes (toxicity), Yellow Nail Syndrome (chemically induced), Yellow Nail Syndrome (diagnosis).
- MESH :
- chemical , analysis : Titanium.
- chemically induced : Bronchiectasis, Maxillary Sinusitis, Yellow Nail Syndrome.
- chemistry : Nails, Toothpastes.
- diagnosis : Bronchiectasis, Maxillary Sinusitis, Yellow Nail Syndrome.
- chemical , toxicity : Titanium, Toothpastes.
- Child, Diagnosis, Differential, Female, Humans.
Abstract
Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence. This patient's titanium exposure may have come from her habit of swallowing children's toothpaste. With meticulous avoidance of swallowing toothpaste, she had amelioration of her yellow nail discoloration as well as diminution of her respiratory symptoms. We reevaluated her nail clippings for titanium 3 years later, and no titanium was detected. This observation suggests that avoiding titanium exposure could alleviate the symptoms of YNS. This is the first report of YNS in a pediatric patient that demonstrates a relationship between YNS and titanium. We review the previous reports of pediatric patients with YNS.
DOI: 10.1542/peds.2016-0546
PubMed: 27940507
Affiliations:
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Le document en format XML
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tsaijd@yahoo.com.tw.</nlm:affiliation><country wicri:rule="url">Taïwan</country><wicri:regionArea>Department of Pediatrics, MacKay Children's Hospital, Taipei</wicri:regionArea><wicri:noRegion>Taipei</wicri:noRegion></affiliation></author></analytic><series><title level="j">Pediatrics</title><idno type="eISSN">1098-4275</idno><imprint><date when="2017" type="published">2017</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bronchiectasis (chemically induced)</term><term>Bronchiectasis (diagnosis)</term><term>Child</term><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term><term>Maxillary Sinusitis (chemically induced)</term><term>Maxillary Sinusitis (diagnosis)</term><term>Nails (chemistry)</term><term>Titanium (analysis)</term><term>Titanium (toxicity)</term><term>Toothpastes (chemistry)</term><term>Toothpastes (toxicity)</term><term>Yellow Nail Syndrome (chemically induced)</term><term>Yellow Nail Syndrome (diagnosis)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Diagnostic différentiel</term><term>Dilatation des bronches ()</term><term>Dilatation des bronches (diagnostic)</term><term>Enfant</term><term>Femelle</term><term>Humains</term><term>Ongles ()</term><term>Pâtes dentifrices ()</term><term>Pâtes dentifrices (toxicité)</term><term>Sinusite maxillaire ()</term><term>Sinusite maxillaire (diagnostic)</term><term>Syndrome des ongles jaunes ()</term><term>Syndrome des ongles jaunes (diagnostic)</term><term>Titane (analyse)</term><term>Titane (toxicité)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Titanium</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>Titane</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Bronchiectasis</term><term>Maxillary Sinusitis</term><term>Yellow Nail Syndrome</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Nails</term><term>Toothpastes</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Bronchiectasis</term><term>Maxillary Sinusitis</term><term>Yellow Nail Syndrome</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Dilatation des bronches</term><term>Sinusite maxillaire</term><term>Syndrome des ongles jaunes</term></keywords><keywords scheme="MESH" type="chemical" qualifier="toxicity" xml:lang="en"><term>Titanium</term><term>Toothpastes</term></keywords><keywords scheme="MESH" qualifier="toxicité" xml:lang="fr"><term>Pâtes dentifrices</term><term>Titane</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Diagnosis, Differential</term><term>Female</term><term>Humans</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Diagnostic différentiel</term><term>Dilatation des bronches</term><term>Enfant</term><term>Femelle</term><term>Humains</term><term>Ongles</term><term>Pâtes dentifrices</term><term>Sinusite maxillaire</term><term>Syndrome des ongles jaunes</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Yellow nail syndrome (YNS) is an uncommon disorder, the classic triad of which consists of yellow nails, lymphedema, and respiratory symptoms. Few pediatric cases have been reported. We report a 9-year-old girl with yellowish nail discoloration for 1 year accompanied by respiratory symptoms, including chronic cough, recurrent pneumonia, bronchiectasis, and chronic sinusitis. The patient was diagnosed with YNS. Knowing that a relationship between YNS and titanium has been reported, we collected her nail clippings and detected titanium in them by energy dispersive radiograph fluorescence. This patient's titanium exposure may have come from her habit of swallowing children's toothpaste. With meticulous avoidance of swallowing toothpaste, she had amelioration of her yellow nail discoloration as well as diminution of her respiratory symptoms. We reevaluated her nail clippings for titanium 3 years later, and no titanium was detected. This observation suggests that avoiding titanium exposure could alleviate the symptoms of YNS. This is the first report of YNS in a pediatric patient that demonstrates a relationship between YNS and titanium. We review the previous reports of pediatric patients with YNS.</div></front></TEI><affiliations><list><country><li>Taïwan</li></country></list><tree><country name="Taïwan"><noRegion><name sortKey="Hsu, Ting Yuan" sort="Hsu, Ting Yuan" uniqKey="Hsu T" first="Ting-Yuan" last="Hsu">Ting-Yuan Hsu</name></noRegion><name sortKey="Chang, Brian Pin Hsuan" sort="Chang, Brian Pin Hsuan" uniqKey="Chang B" first="Brian Pin-Hsuan" last="Chang">Brian Pin-Hsuan Chang</name><name sortKey="Lee, Ming Dar" sort="Lee, Ming Dar" uniqKey="Lee M" first="Ming-Dar" last="Lee">Ming-Dar Lee</name><name sortKey="Lin, Chun Chen" sort="Lin, Chun Chen" uniqKey="Lin C" first="Chun-Chen" last="Lin">Chun-Chen Lin</name><name sortKey="Tsai, Jeng Daw" sort="Tsai, Jeng Daw" uniqKey="Tsai J" first="Jeng-Daw" last="Tsai">Jeng-Daw Tsai</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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